However, using the Fugl–Meyer Life satisfaction Check List scores, 50% were shown to be satisfied with their sexual life. Taking the series of patients treated in the same institution between 1986 and 2000, Windahl et al. (16) concluded that most

men treated with laser for localized cancer of the penis resume to be sexually active at a level equivalent to that before treatment, with good overall satisfaction concerning their sexual life. However, these data are single centered, and it seems premature to conclude the impact of laser ablation. The first detailed analysis of the impact of PB on the functions of the penis and sexual behavior has several limitations. First, sexuality is an area highly dependent on sociocultural elements. The findings

Daporinad clinical trial Selleckchem 3 Methyladenine on the impact of PB of the penis on sex were obtained only from the French men. Therefore, it may be difficult to extrapolate to other cultures, including the Spanish Catalonian population. In addition, because of the low incidence of this disease in Europe, the size of our study population was relatively small, which limits our ability to achieve a detailed analysis, including subgroups (young males, circumcised patients, gay, and so on). In the absence of a control group, it is impossible to compare the results of PB with other treatments of localized cancer of the penis, in particular, partial penectomy (17) and laser ablation and whether PB causes less sexual ioxilan dysfunction than the latter.

For the methodology, although we have chosen the form of self-administered questionnaire, followed by an interview so that the patients are not influenced in their responses or misunderstand the questions, we cannot rule out the subjectivity of responses. In addition, the use of the IIEF in this population is quite questionable because it is a poor score that applies to a population with few penetrating sexual reports. For this reason, we have completed a questionnaire specifically designed for the study. However, the conclusions drawn from it must be taken with caution; this questionnaire has not been previously subject to a validation study. Therefore, these results should therefore be considered as preliminary data, which need to be confirmed with a larger scale study. Recently, a consensus guideline was developed between the American Brachytherapy Society and Groupe Européen de Curiethérapie/European Society for Therapeutic Radiation and Oncology for the use of brachytherapy in the primary management of carcinoma of the penis. The good tumor control rates, acceptable morbidity, and functional organ preservation warrant recommendation of brachytherapy as the initial treatment for invasive T1, T2, and selected T3 penile cancers (18). After treatment, most patients reported that PB has little or no effect on their sexuality.