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local oxidation nanolithography. Nanotechnology 2009, 20:125302. 10.1088/0957-4484/20/12/12530219420463CrossRef Competing interests The authors declare that they have no competing interests. Authors’ contributions All authors carried out the growth of the samples, analysis of the results, and drafted the manuscript. DF carried out the measurements. All authors read and approved the final manuscript.”
“Background Magnetic nanoparticles have found a multitude of applications in biomedical research, such as radiological contrast agents, magnetic hyperthermia treatment modalities, nanomedicine, and targeted drug delivery of cancer agents (e.g., paclitaxel) to name a few [1–4]. Magnetic nanoparticles are mainly classified into three different categories: (a) metal oxide nanoparticles such as iron oxides, which are not very strong magnetically, but stable in solution [5]; (b) metallic nanoparticles which are magnetically strong but unstable in solution [5]; and (c) metal alloys such as iron-platinum nanoparticles and cobalt-platinum nanoparticles which have high magnetic properties and are also stable in solution [5]. In addition to biocompatibility, biomedical applications require the nanoparticles to be stable eltoprazine in harsh ionic in vivo environments

such as human sera and plasma solutions. The nature of the magnetic nanoparticle surface determines the important properties such as biocompatibility and stability in solutions. Magnetic nanoparticles can be synthesized through a multitude of methods including alkaline solution precipitation, thermal decomposition, microwave heating methods, sonochemical techniques, spray pyrolysis, and laser pyrolysis to name a few [1, 4, 6, 7]. Of all the methods, thermal decomposition of organometallic iron in organic liquids provides the most reliable means of nanoparticle synthesis with good control over the size and shape of the particles [1, 6, 7]. Thermal decomposition methods yield particles that are more crystalline and uniform in shape ranging from 3 to 60 nm in diameter [1, 4, 7].