The strain formed smooth yellow colonies on R2A plates. Growth occurred at 10-37 degrees C (optimum, 30-37 degrees C), at pH 6.0-10.0 (optimum, pH 7.0-9.0) and in the presence of 0-1% NaCl (optimum, 0 %). Catalase test was positive and oxidase test was negative. Ubiquinone 10 (010) was the major respiratory quinone. C(18 : 1)omega 7c and C(17 : 1)omega 6c were the most abundant fatty acids. Diphosphatidylglycerol, phosphatidylethanolamine and phosphatidylglycerol were the major polar lipids. The DNA G + C content of strain JM27(T) was 66.4 mol%. The 16S rRNA gene sequence of the isolate showed highest similarity to that of Altererythrobacter

marinus H32(T) (96.4%). Phylogenetic analysis based on 16S rRNA gene sequences indicated that the strain belonged to the genus Altererythrobacter Selleckchem Emricasan of the family Erythrobacteraceae of the class Alphaproteobacteria. On the basis of phylogenetic analysis, whole-cell fatty acids, polar lipid compositions, and biochemical and physiological characteristics, strain JM27(T) is proposed to represent a novel species of the genus Altererythrobacter for which the name Altererythrobacter dongtanensis sp. nov. is proposed. The type strain is JM27(T) (=KCTC 22672(T) = CCTCC AB 209199(T)).”
“Background

This study was carried out to determine the role of plasma EpsteinBarr virus (pEBV)-DNA and positron-emission tomography (PET)-CT scan in predicting the outcome of nasopharyngectomy and cervical lymphadenectomy for recurrent nasopharyngeal carcinoma QNZ molecular weight (NPC).\n\nMethods. Between 2007 and 2009, we recruited patients who had local or regional recurrent NPC after radiotherapy. The relationship between preoperative pEBV-DNA level, maximal standard uptake value (SUVmax), and surgical outcome was analyzed.\n\nResults. Forty-two patients had local tumor recurrence. Their median pEBV-DNA level and SUVmax were 348 copies

and 4.7, respectively. Both values were significantly lower than those with palliative nasopharyngectomy. Twenty-two patients had regional failure. Their mean pEBV-DNA level and tumor SUVmax were 626 copies and 7.6, respectively. The metastatic lymph nodes with extracapsular spread had a significantly higher mean SUVmax.\n\nConclusions. Preoperative pEBV-DNA and PET-CT predict the surgical outcome of nasopharyngectomy AMN-107 for recurrent NPC. Similarly, PET-CT scan predicts the presence of extracapsular spread of metastatic lymph nodes. These patients may warrant further postoperative adjuvant therapy. (C) 2011 Wiley Periodicals, Inc. Head Neck 34: 541-545, 2012″
“Cognitive and olfactory impairments have previously been demonstrated in patients with spinocerebellar ataxia type 3 (SCA3), also known as Machado-Joseph disease (MJD)-SCA3/MJD. We investigated changes in regional cerebral blood flow (rCBF) using single-photon emission computed tomography (SPECT) imaging in a cohort of Brazilian patients with SCA3/MJD.